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Possible food and drug interactions when taking this medication
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)
|
What special precautions should I follow?
Herpes infection of the genitals can be caught from or spread to your partner during any sexual activity. Even though you may get herpes if your partner has no symptoms, the infection is more likely t
o be spread if sores are present. This is true until the sores are completely healed and the scabs have fallen off. Therefore, it is best to avoid any sexual activity if either you or your sexual part
ner has any symptoms of herpes. The use of a latex condom (ˇ§rubberˇ¨') may help prevent the spread of herpes. However, spermicidal (sperm-killing) jelly or a diaphragm will probably not help.
|
How should this medicine be used?
This medication is used to treat herpes infections of the skin, mouth, mucous membranes, genital herpes, herpes zoster (shingles), and chickenpox in some individuals. This medication does not cure her
pes, but relieves the pain and may make the infection clear faster.
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What special precautions should I follow?
Use a condom during sexual intercourse. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy.
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Side Effects
Parenteral:
1. Renal toxicity; precipitation of acyclovir crystals can occur in renal tubules if the maximum solubility of free acyclovir (2.5mg/ml at 37?C in water) is exceeded or if the drug is
given by bolus injection. Serum creatinine and BUN rise and creatinine clearance decreases.
2. Encephalopathic changes: Approximately 1% of patients receiving IV acyclovir manifested encephalopath
ic changes characterized by lethargy, obtundation, tremors, confusion, hallucinations, agitation, seizures or coma.
3. Other: transient elevation of serum creatinine; rash or hives; diaphoresis; h
ematuria; hypotension; headache and nausea; thrombocytosis.
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Overdose
Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness ˇK
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