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DRUG ABUSE AND DEPENDENCE :
When you are taking buspirone, it is especially important that your health care professional know if you are taking any of the following:
- Erythromycin (e.g., ERYC, E.E.S.) or
- Itraco
nazole (e.g., Sporanox)¡XHigher blood levels of buspirone may occur, increasing the chance of side effects. Your doctor may change the dose of buspirone that you take
- Monoamine oxidase (MAO) i
ibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline at doses more than 10 mg a day [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X
aking buspirone while you are taking monoamine oxidase (MAO) inhibitors may cause high blood pressure
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Why is this medication prescribed?
Buspirone (byoo-SPYE-rone) is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of every
day life.
It is not known exactly how buspirone works to relieve the symptoms of anxiety. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in
certain parts of the brain.
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Special Wanring
Post Introduction Clinical Experience:
Post-marketing experience in the US has shown an adverse experience profile similar to that given above. Additional reports have included rare occurrences of
allergic reaction, cogwheel rigidity, dystonic reaction, ecchymosis, emotional lability and tunnel vision. Because of the uncontrolled nature of these spontaneous reports, a causal relationship to bu
spirone treatment has not been determined.
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Before Using This Medicine
Occupational Hazards:
Until further experience is obtained with buspirone, patients should be warned not to operate an automobile or undertake activities requiring mental alertness, judgment and p
hysical coordination, until they are reasonably certain that buspirone does not affect them adversely.
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What side effects may occur?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your
doctor as soon as possible if any of the following side effects occur:
Chest pain; confusion; fast or pounding heartbeat; fever; incoordination; mental depression; muscle weakness; num
bness, tingling, pain, or weakness in hands or feet; skin rash or hives; stiffness of arms or legs; sore throat; uncontrolled movements of the body
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Proper Use of This Medicine
Buspirone comes as a tablet to take by mouth. It usually is taken two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any
part you do not understand. Take buspirone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Continue to take buspirone even if you fe
el well. Do not stop taking buspirone without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will decrease your dose gradually. This drug must b
e taken regularly for a few weeks before its full effect is felt.
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