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Overdosage
Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amou
nt of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like cof
fee grounds; weight gain
- lack of energy
- drowsiness
- upset stomach
- vomiting
- stomach pain
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Before Using This Medicine
Remember to tell your doctor about any stomach ulcers or bleeding you've had in the past. Also alert your doctor if you develop any digestive problems, swelling, or rash.
If you have asthma,
use Celebrex with caution. It could trigger an attack, especially if you are also sensitive to aspirin.
If you are taking a steroid medication for your arthritis, do not discontinue it abru
ptly when you begin therapy with Celebrex. Celebrex is not a substitute for such drugs.
If you are prone to anemia (loss of red blood cells), make sure the doctor knows about it. Celebrex oc
casionally fosters this problem.
The safety and effectiveness of Celebrex have not been tested in children under 18.
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How should this medicine be used?
Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any par
t you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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What is this Drug
Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. It is the first of a new class of nonsteroidal anti-inflammatory drug
s (NSAIDs) called "COX-2 inhibitors." Like older NSAIDs such as Motrin and Naprosyn, Celebrex is believed to fight pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unli
ke the older medications, however, it does not interfere with a similar substance, called COX-1, which exerts a protective effect on the lining of the stomach. Celebrex is therefore less likely to cau
se the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.
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Possible Side Effect
Rare side effects may include:
- heart failure, heart irregularities, hemorrhoids, hepatitis, hernia of the stomach, herpes infection, hives, hot flashes, increased appetite, increased blood pre
ssure, increased heart rate, increased muscle tone, increased urination, infection, inflammation of the digestive tract, inflammation of the bladder, inflammation of the blood vessels, intestinal blee
ding, intestinal obstruction or perforation, itching, jaundice, joint pain or inflammation, kidney problems, laryngitis, leg cramps, liver problems,
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Possible food and drug interactions when taking this medication
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c
hange the dose, or other precautions may be necessary. When you are taking celecoxib, it is especially important that your health care professional know if you are taking any of the following:
- Aspirin or
- Fluconazole (e.g., Diflucan)¡XThe chance of serious side effects may be increased
- Lithium (e.g., Lithane)¡XHigher blood levels of celecoxib and an increased chance of si
effects may occur
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