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Precautions while Using this Medicine
It is important that your doctor check your progress at regular visits. This will allow your doctor to check for any unwanted effects.

If your symptoms do not improve within a few weeks (or m onths for some infections), or if they become worse, check with your doctor.

These medicines should notbe taken with astemizole (e.g., Hismanal), cisapride (e.g., Propulsid),dofetilide (e.g., Tikosyn) or terfenadine (e.g., Seldane). Doing so may increase the risk of serious side effects affecting the heart.

Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

Symptoms of Diflucan overdose may include:
- Hallucinations , paranoia

How to Use
Fluconazole comes as a tablet and liquid to take by mouth. It is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Continue to take fluconazole even if you feel well. Do not stop taking fluconazole without talking to your doctor.

What special precautions should I follow?
The presence of other medical problems may affect the use of Diflucan. Make sure you tell your doctor if you have any other medical problems, especially:
- Congestive heart failure¡XItraconazole m ay slow down the heart rhythm and make heart failure worse.
- Achlorhydria (absence of stomach acid) or
- Hypochlorhydria (decreased amount of stomach acid)¡XItraconazole and ketoconazole may not be absorbed from the stomach as well in patients who have low levels of or no stomach acid
- Alcohol abuse (or history of) or
- Liver disease¡XAlcohol abuse or liver disease may increase the chance of side effects caused by Diflucan
- Kidney disease¡XThe effects of fluconazole may be increased in patients with kidney disease

Possible food and drug interactions when taking this medication
When you are taking Diflucan, it is especially important that your health care professional know if you are taking any of the following:

- Etretinate (e.g., Tegison) or
- Gold salts (me dicine for arthritis) or
- Hydroxychloroquine (e.g., Plaquenil) or
- Mercaptopurine (e.g., Purinethol) or
- Methotrexate (e.g., Mexate) or
- Methyldopa (e.g., Aldomet) or
- Na ltrexone (e.g., Trexan) (with long-term, high-dose use) or
- Oral contraceptives (birth control pills) containing estrogen or
- Other anti-infectives by mouth or by injection (medicine for i nfection) or
- Plicamycin (e.g., Mithracin) or

Why is this drug prescribed?
Although these uses are not included in product labeling, Diflucan are used in certain patients with the following medical conditions:

- Cryptococcosis
- Cushing's syndrome
- Febri le neutropenia
- Fungus infections in newborns
- Hirsutism
- Histoplasmosis
- Paronychia (infection of the tissue surrounding the nail)
- Penicillium marneffei infection
- Pneumonia caused by fungus
- Prostate cancer
- Ringworm of the beard, hand, or scalp
- Septicemia (infection of the blood) caused by fungus
- Skin infection (including leishmania sis and sporotrichosis)


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