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What Is It
Butalbital and acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen) combination is a pain reliever and relaxant. It is used to treat tension headaches. Butalbital belongs to the group of medicines called barbiturates (bar-BI-tyoo-rates) . Barbiturates act in the central nervous system (CNS) to produce their effects.

When you take butalbital for a long time, your body may get used to i t so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Before Using This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Drug abuse or dependence¡XDependence on butalbital may develop; also, acetaminophen ma cause liver damage in people who abuse alcohol
- Asthma, emphysema, or other chronic lung disease or
- Hepatitis or other liver disease or
- Hyperactivity (in children) or
- Kidne y disease¡XThe chance of serious side effects may be increased
- Diabetes mellitus (sugar diabetes) or
- Mental depression or
- Overactive thyroid or
- Porphyria¡XButalbital can ma these conditions worse
- Heart disease (severe)¡XThe caffeine in some butalbital and acetaminophen combinations can make some kinds of heart disease worse

Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.

Cautions
This medicine may cause some people to become drowsy, dizzy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangero us if you are dizzy or are not alert and clearheaded.

Possible food and drug interactions when taking this medication
Do not take acetamino phenbutalbital caffeine - Esgic if you have taken monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the las t 14 days. Dangerous side effects could result. Acetaminophen and butalbital may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedative s (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants.

How to Use
This medicine will relieve a headache best if you take it as soon as the headache begins. If you get warning signs of a migraine, take this medicine as soon as you are sure that the migraine is coming . This may even stop the headache pain from occurring. Lying down in a quiet, dark room for a while after taking the medicine also helps to relieve headaches.


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