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Overdosage
Seek emergency medical attention. Symptoms of an acetamino phenbutalbita lcaffeine - Esgic overdose include insomnia, restlessness, tremor, nausea, vomiting, diarrhea, abdominal pain, sweating, seizur es, drowsiness, decreased breathing,

Before Using This Medicine
Older adultsˇX

- For butalbital: Certain side effects, such as confusion, excitement, or mental depression, may be especially likely to occur in elderly patients, who are usually more sensit ve than younger adults to the effects of the butalbital in this combination medicine.
- For acetaminophen: Acetaminophen has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.
- For caffeine: There is no specific information comparing use of caffeine in the elderly with use in other age groups

Cautions
Check with your doctor:

If the medicine stops working as well as it did when you first started using it. This may mean that you are in danger of becoming dependent on the medicine. Do not tr y to get better pain relief by increasing the dose.

If you are having headaches more often than you did before you started taking this medicine. This is especially important if a new headach e occurs within 1 day after you took your last dose of this medicine, headaches begin to occur every day, or a headache continues for several days in a row. This may mean that you are dependent on the medicine. Continuing to take this medicine will cause even more headaches later on. Your doctor can give you advice on how to relieve the headaches.

What Is It
Esgic contains Acetaminophen / butalbital / caffeine. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates that slow down your central nervous syst em (brain and nerve impulses) causing relaxation. Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine ar e used to relieve complex tension (muscle contraction) headaches although precisely how it works is unknown.

Significant Interactions:
When you are taking a butalbital and acetaminophen combination, it is especially important that your health care professional know if you are taking any of the following:

- Anticoagulants (b lood thinners), or
- Carbamazepine (e.g., Tegretol) or
- Contraceptives, oral (birth control pills) containing estrogen, or
- Corticosteroids (cortisone-like medicines) or
- Cortic otropin (e.g., ACTH)ˇXButalbital may make these medicines less effective

What side effects may occur?
If you experience any of the following serious side effects, stop taking acetaminophenbutalbitalcaffeine and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of yo ur throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, sev ere fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst,


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