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Description
Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caff eine is believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine are used to relieve complex tension (muscle contraction) headaches although precisely how it works is unknown. Acetaminophen / butalbital / caffeine may also be used for purposes other than those listed in this medication guide.

Drug Interactions
Butalbital slows the central nervous system (CNS) and intensifies the effects of alcohol and other CNS depressants. Use of alcohol with this drug may also cause overdose symptoms. Avoid alcoholic beve rages while taking Fioricet.

It is especially important to check with your doctor before combining Fioricet with the following:

- Antihistamines such as Benadryl
- Drugs known as monoamine oxidase inhibitors, including the antidepressants Nardil and Parnate
- Drugs to treat depression such as Elavil
- Major tranquilizers such as Haldol and Thorazine
- Muscle relaxants such as Flexeril
- Narcotic pain relievers such as Darvon
- Sleep aids such as Halcion
- Tranquilizers such as Xanax and Valium

Precautions while Using this Medicine
Before you have any medical tests, tell the person in charge that you are taking this medicine. Caffeine (present in some butalbital and acetaminophen combinations) interferes with the results of cert ain tests that use dipyridamole (e.g., Persantine) to help show how well blood is flowing to your heart. Caffeine should not be taken for 8 to 12 hours before the test. The results of other tests may also be affected by butalbital and acetaminophen combinations.

Symptoms of overdose may include:
Seek emergency medical attention. Symptoms of an acetaminophen / butalbital / caffeine - Fioricet overdose include insomnia, restlessness, tremor, nausea, vomiting, diarrhea, abdominal pain, sweating, seizures, drowsiness, decreased breathing,

Side Effects
If you experience any of the following serious side effects, stop taking acetaminophen / butalbital / caffeine - Fioricet and seek emergency medical attention: an allergic reaction (difficulty breathi ng; closing of your throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleedin g or bruising, severe fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst,

Proper Use of This Medicine
Take acetaminophen / butalbital / caffeine - Fioricet exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take acetaminophen / butalbital / caffeine with food or milk if it upsets your stomach. Never take more acetaminophen / butalbital / caffeine than is prescribed f or you. If your pain is not being adequately treated, talk to your doctor. Store acetaminophen / butalbital / caffeine at room temperature away from moisture and heat.


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