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What is this medicine
Some butalbital and acetaminophen combinations also contain caffeine (KAF-een) . Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain a s determined by your doctor.

Drug Interactions
It is especially important that your health care professional know if you are taking any of the following:

- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [ e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)¡XThese medicines may add to the effects of butalbital and increase the chance of drowsiness or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)¡XThe chance of side effects may be increased

Precautions while Using this Medicine
Before you have any medical tests, tell the person in charge that you are taking this medicine. Caffeine (present in some butalbital and acetaminophen combinations) interferes with the results of cert ain tests that use dipyridamole (e.g., Persantine) to help show how well blood is flowing to your heart. Caffeine should not be taken for 8 to 12 hours before the test. The results of other tests may also be affected by butalbital and acetaminophen combinations.

How should you take this medication?
Take acetaminophen / butalbital / caffeine - Fioricet exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take acetaminophen / butalbital / caffeine with food or milk if it upsets your stomach. Never take more acetaminophen / butalbital / caffeine than is prescribed f or you. If your pain is not being adequately treated, talk to your doctor. Store acetaminophen / butalbital / caffeine at room temperature away from moisture and heat.

Symptoms of overdose may include:
Symptoms of Fioricet overdose can be due to its barbiturate or its acetaminophen component.

Symptoms of barbiturate poisoning may include:
- Coma, confusion, drowsiness, low blood press ure, shock, slow or troubled breathing

Overdose due to the acetaminophen component of Fioricet may cause kidney and liver damage, blood disorders, or coma due to low blood sugar. Massive dos es may cause liver failure.

Symptoms of liver damage include:
- Excess perspiration, feeling of bodily discomfort, nausea, vomiting

What special precautions should I follow?
Before taking acetaminophen, butalbital, and caffeine,

tell your doctor and pharmacist if you are allergic to acetaminophen, butalbital, caffeine, or any other drugs.
tell your doctor if you have or have ever had liver disease, porphyria, or depression.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking this medication, call your doctor.
you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
remember that alcohol can add to the drowsiness caused by this drug.


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