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What side effects may occur?
If you experience any of the following serious side effects, stop taking acetaminophen / butalbital / caffeine - Fioricet and seek emergency medical attention: an allergic reaction (difficulty breathi
ng; closing of your throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleedin
g or bruising, severe fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst,
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Significant Interactions:
Do not take acetaminophen / butalbital / caffeine -Fioricet if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in
the last 14 days. Dangerous side effects could result. Acetaminophen and butalbital may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines,
sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your do
ctor approves. Many other medicines contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Too much acetaminophen can be very dangerous. Drugs other than those
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How should you take this medication?
People who get a lot of headaches may need to take a different medicine to help prevent headaches. It is important that you follow your doctor's directions about taking the other medicine, even if you
r headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headach
es should occur less often, and they should be less severe and easier to relieve than before. This will reduce the amount of headache relievers that you need. If you do not notice any improvement afte
r several weeks of headache-preventing treatment, check with your doctor.
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Why is this drug prescribed?
Butalbital and acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen) combination is a pain reliever and relaxant. It is used to treat tension headaches. Butalbital belongs to the group of medicines
called barbiturates (bar-BI-tyoo-rates) . Barbiturates act in the central nervous system (CNS) to produce their effects.
When you take butalbital for a long time, your body may get used to i
t so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is
used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.
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Precautions Before Using This Medicine
PregnancyˇX
- For butalbital: Barbiturates such as butalbital have been shown to increase the chance of birth defects in humans. Also, one study in humans has suggested that barbiturates tak
n during pregnancy may increase the chance of brain tumors in the baby.Butalbital may cause breathing problems in the newborn baby if taken just before or during delivery.
- For acetaminophen: Al
though studies on birth defects with acetaminophen have not been done in pregnant women, it has not been reported to cause birth defects or other problems.
- For caffeine: Use of large amounts of
caffeine during pregnancy may cause problems with the heart rhythm and the growth of the fetus.
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