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Precautions Before Using This Medicine
Before taking acetaminophen, butalbital, and caffeine,
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thin
ners') such as warfarin (Coumadin), antidepressants, antihistamines, pain medications, sedatives, sleeping pills, tranquilizers, and vitamins. Many nonprescription pain relievers contain acetaminophen
. Too much of this drug can be harmful.
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Other Medicines
It is especially important that your health care professional know if you are taking any of the following:
- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)ˇXThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)ˇXThe chance of side effects may be increased
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What Is It
Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caff
eine is believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine are used to relieve complex tension (muscle contraction)
headaches although precisely how it works is unknown. Acetaminophen / butalbital / caffeine may also be used for purposes other than those listed in this medication guide.
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Overdose
Symptoms of Fioricet overdose can be due to its barbiturate or its acetaminophen component.
Symptoms of barbiturate poisoning may include:
- Coma, confusion, drowsiness, low blood press
ure, shock, slow or troubled breathing
Overdose due to the acetaminophen component of Fioricet may cause kidney and liver damage, blood disorders, or coma due to low blood sugar. Massive dos
es may cause liver failure.
Symptoms of liver damage include:
- Excess perspiration, feeling of bodily discomfort, nausea, vomiting
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Special warnings about this medication
The butalbital in this medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressant
s are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine; narcotics; other barbiturates; medicine for
seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Also, drinking large amounts of alcoholic beverages regularly while taking this medicine may increase the chance of live
r damage, especially if you take more of this medicine than your doctor ordered or if you take it regularly for a long time.
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How should this medicine be used?
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If butalbital and acetaminophen co
mbination is taken regularly (for example, every day), it may become habit-forming (causing mental or physical dependence). The caffeine in some butalbital and acetaminophen combinations can also incr
ease the chance of dependence. Dependence is especially likely to occur in patients who take these medicines to relieve frequent headaches. Taking too much of this medicine may also lead to liver dama
ge or other medical problems.
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