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Drug Interactions
Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially other prescription medicine for migraine headaches, or if y ou smoke tobacco.

When you are taking .Imitrex, it is especially important that your health care professional know if you are taking the following:

Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡XTaking .Imitrex while you are taking r within 2 weeks of taking MAO inhibitors may cause sudden high body temperature, extremely high blood pressure and severe convulsions;

Cautions
Check with your doctor if you have used .Imitrex for three headaches, and have not had good relief. Also, check with your doctor if your migraine headaches are worse, or if they are occurring more oft en, than before you started using .Imitrex.

Drinking alcoholic beverages can make headaches worse or cause new headaches to occur. People who suffer from severe headaches should probably avoi d alcoholic beverages, especially during a headache.

Some people feel drowsy or dizzy during or after a migraine, or after taking .Imitrex to relieve a migraine. As long as you are feeling dr owsy or dizzy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

What is this Drug
Imitrex ( Sumatriptan ) is a headache medicine. It is believed to work by causing vasoconstriction (narrowing) of arteries and veins that supply blood to your head. Imitrex ( Sumatriptan ) tablets and injections are used to treat vascular headaches such as migraine and cluster headaches. Imitrex ( Sumatriptan ) will not prevent migraines or cluster headaches or reduce the number of attacks. It wil l only treat a migraine or cluster headache that is already occurring. Imitrex ( Sumatriptan ) may also be used for purposes other than those listed in this medication guide.

Before Using This Medicine
Do not take Imitrex ( Sumatriptan ) if the headache you are experiencing is not like other migraines that you have had. Do not take this medication if you have heart disease including angina (chest pa in), history of a heart attack, or high blood pressure. Serious, even fatal, side effects involving the heart have been reported with Imitrex ( Sumatriptan ). Never take more of this medication than i s prescribed by your doctor. More medication will not further treat symptoms. If your symptoms are not being treated, contact your doctor.

Possible Side Effect
Less common or rare side effects may include:
- Abdominal discomfort, agitation, allergic reactions (severe), anxiety, asthma, backache, backflow of stomach contents, bleeding between periods, bl eeding in ears, nose or throat, breast tenderness, burning/numbness of tongue, changes in heart rhythm, chills, cold sensation, confusion, constipation, cough, depression, diarrhea, difficult or labor ed breathing, difficult or painful urination, difficulty concentrating, difficulty speaking, difficulty swallowing, drowsiness/calmness, dry mouth, ear infection, ear pain, exaggerated feeling of well -being, eye irritation, facial pain, fainting, fatigue, feeling strange, fever, general feeling of illness, headache, hearing loss, hearing disturbance,

Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor


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