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Side Effects
Although side effects from .Imitrex are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- flushing
- tingling feeling
- feeling of warmth or heaviness
- drowsiness
- dizziness
- upset stomach
- diarrhea
- vomiting
- irritation of the nose
- muscle cramps

If you experience any of the following symptoms, call your doctor immediately:

- pain or tightness in chest or throat
- sudden or severe stomach pain
- fast heartbeat
- difficulty breathing
- wheezi ng
- redness, swelling, or itching of the eyelids, face, or lips
- skin rash, lumps, or hives
- change in vision

How should you take this medication?
Your doctor may direct you to take another medicine to help prevent headaches. It is important that you follow your doctor's directions, even if your headaches continue to occur. Headache-preventing m edicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headaches should occur less often, and they should be less severe and easier to relieve. This can reduce the amount of sumatriptan or pain relievers that you need. If you do not notice any improvement after several weeks of headache-preventing treatment, chec k with your doctor.

Symptoms of overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Proper Use of This Medicine
Imitrex tablets should be swallowed whole, with liquid. If you have had no relief 2 hours after taking Imitrex Tablets, you may take a second dose of up to 100 milligrams, if your doctor advises it. I f the headache returns, you may take additional doses at intervals of at least 2 hours. You should not take more than 300 milligrams in one day. If your headache returns after you have had an Imitrex Injection, you may take single Imitrex Tablets, at intervals of at least 2 hours, up to a maximum of 200 milligrams in a day.

Imitrex nasal spray is packaged in single-dose bottles containin g either 5 or 20 milligrams of the drug. The usual dosage is a single spray in one nostril.

Drug Interactions
Do not take Imitrex ( Sumatriptan ) if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. T he combination could cause seizures, nausea, vomiting, sweating, flushing,

Special warnings about this medication
tell your doctor if you smoke, if you have a strong family history of heart disease, if you are postmenopausal, or if you are a man over 40. Also tell your doctor if you have or have ever had high blo od pressure; angina (recurring chest pain); a heart attack; diabetes; high cholesterol; obesity; stroke; transient ischemic attack (mini-stroke); ischemic bowel disease; coronary artery disease; seizu res; or blood vessel, kidney, or liver disease.


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