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Significant Interactions:
Do not take Imitrex ( Sumatriptan ) if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. T he combination could cause seizures, nausea, vomiting, sweating, flushing,

Side Effects of This Medicine
If you experience any of the following serious side effects, stop taking Imitrex ( Sumatriptan ) and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throa t; swelling of your lips, tongue, or face; or hives); or severe or prolonged chest pain or an irregular heartbeat. Other, less serious side effects may be more likely to occur. Continue to take Imitre x ( Sumatriptan ) and talk to your doctor if you experience nausea; drowsiness

How to Use
Do not use .Imitrex for a headache that is different from your usual migraines . Instead, check with your doctor.

To relieve your migraine as soon as possible, use .Imitrex as soon as the hea dache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using .Imitrex. Using .Imitrex during the aura probably will no t prevent the headache from occurring. However, even if you do not use .Imitrex until your migraine has been present for several hours, the medicine will still work.

Lying down in a quiet, da rk room for a while after you use this medicine may help relieve your migraine.

How should you take this medication?
.Imitrex comes as a tablet to take by mouth and a nasal spray. It should be used at the first sign of a migraine headache. If you are at risk for heart disease and you have never taken .Imitrex before , you may need to take the first dose in your doctor's office. Usually only one dose is needed. If pain is not relieved with the first dose, your doctor may prescribe a second dose to be taken after a t least 2 hours. Do not take more than 200mg of the tablets or 40 mg of the nasal spray in any 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharma cist to explain any part you do not understand. Take .Imitrex exactly as directed.

Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Cautions
tell your doctor if you smoke, if you have a strong family history of heart disease, if you are postmenopausal, or if you are a man over 40. Also tell your doctor if you have or have ever had high blo od pressure; angina (recurring chest pain); a heart attack; diabetes; high cholesterol; obesity; stroke; transient ischemic attack (mini-stroke); ischemic bowel disease; coronary artery disease; seizu res; or blood vessel, kidney, or liver disease.


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