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How should this medicine be used?
.Imitrex comes as a tablet to take by mouth and a nasal spray. It should be used at the first sign of a migraine headache. If you are at risk for heart disease and you have never taken .Imitrex before , you may need to take the first dose in your doctor's office. Usually only one dose is needed. If pain is not relieved with the first dose, your doctor may prescribe a second dose to be taken after a t least 2 hours. Do not take more than 200mg of the tablets or 40 mg of the nasal spray in any 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharma cist to explain any part you do not understand. Take .Imitrex exactly as directed.

How should this medicine be used?
If you feel much better after a dose of sumatriptan, but your headache comes back or gets worse after a while, you may use more sumatriptan. However, use this medicine only as directed by your doctor. Do not use more of it, and do not use it more often, than directed. Using too much sumatriptan may increase the chance of side effects.

What special precautions should I follow?
Older adults¡XThis medicine has been tested in a limited number of patients between 60 and 65 years of age. It did not cause different side effects or problems in these patients than it did in younger adults. However, there is no specific information comparing use of .Imitrex in patients older than 65 years of age with use in younger adults.

Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Significant Interactions:
If Imitrex is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is important to check with your doctor before combining Imitrex with the following:

- Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate
- Ergot-containing drugs such as Cafergot and Ergostat
- Fluoxetine (Prozac)
- Fluvoxamine ( Luvox)
- Paroxetine (Paxil)
- Sertraline (Zoloft)

Side Effects of This Medicine
If your headache does not feel like any you have been experiencing, do not take Imitrex.

Use Imitrex cautiously if you have liver or kidney disease. Also, if you have any trouble with your e yes, tell your doctor.

Imitrex is not recommended for adults over 65. It has not been tested in children.

Although very rare, severe and even fatal allergic reactions have occurred in people taking Imitrex. Such reactions are more likely in people who have several allergies. In rare cases, people have suffered seizures after taking Imitrex.


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