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What side effects may occur?
Abuse of a .Ionamin (taking the medicine in larger doses or taking it more frequently or for a longer time than the doctor ordered) can cause the following side effects:

Changes in personali ty; excessive, excited activity; irritability (severe); mental illness (severe), similar to schizophrenia; skin disease; trouble in sleeping

Other Medicines
The presence of other medical problems may affect the use of appetite suppressants. Make sure you tell your doctor if you have any other medical problems, especially:
Alcohol abuse (or history of ) or
- Drug abuse or dependence (or history of)¡XDependence on appetite suppressants may be more likely to develop
- Diabetes mellitus (sugar diabetes)¡XThe amount of insulin or oral antidia tic medicine that you need to take may change
- Epilepsy¡XDiethylpropion may increase the risk of having seizures
- Family history of mental illness¡XMental depression or other mental illnes may be more likely to occur

Symptoms of overdose
Abdominal or stomach cramps; coma; confusion; convulsions (seizures); diarrhea (severe); dizziness, lightheadedness, or fainting; fast breathing; feeling of panic; fever; hallucinations (seei ng, hearing or feeling things that are not there); high or low blood pressure; hostility with urge to attack; irregular heartbeat; nausea or vomiting (severe); overactive reflexes; restlessness; trembling or shaking; tiredness, weakness, and mental depression following effects of excitement

How should you take this medication?
This medication is best taken on an empty stomach; one hour before breakfast each morning. Sustained-release or long acting products such as this, must be swallowed whole. Crushing or chewing them wil l destroy the long action and may cause increased side effects. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended.

Precautions Before Using This Medicine
Before taking .Ionamin,

- tell your doctor and pharmacist if you are allergic to .Ionamin or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medi cations you are taking, especially fluoxetine (Prozac), fluvoxamine (Luvox), guanethidine, insulin, MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)] even if you stopped taking them w ithin the past 2 weeks, medications for weight loss and depression, paroxetine (Paxil), sertraline (Zoloft),and vitamins.
- tell your doctor if you have or have ever had heart disease, high blood pressure, arteriosclerosis (narrowing of the arteries), hyperthyroidism (overactive thyroid gland), diabetes, glaucoma, or a history of drug abuse.

Description
Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. IONAMIN is the only medicine of th is class that is set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, othe rs do not.


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