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What special precautions should I follow?
Before using Nexium,

- tell your doctor and pharmacist if you are allergic to Nexium, omeprazole (Prilosec), lansoprazole (Prevacid), or any other drugs.
- tell your doctor and pharmacis t what prescription and nonprescription medications you are taking, especially iron supplements or vitamins that contain iron, ketoconazole (Nizoral), digoxin (Lanoxin), and herbal products.
- te ll your doctor if you have or have ever had liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using Nexium, call your doctor immediately.

What is this medicine
Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)+m-a condition known as gastroesophageal reflux disease. It is also pre scribed to heal the damage (erosive esophagitis) that reflux disease can cause.

Prescribed in combination with the antibiotics Biaxin and Amoxil, Nexium is also used to treat the infection t hat causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach).

Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.

Side Effects of This Medicine
More common side effects may include:
Abdominal pain, diarrhea, headache

How should you take this medication?
If you cannot swallow the capsule, add one tablespoon of cool, soft applesauce to an empty bowl, open one Nexium capsule, and carefully sprinkle the pellets onto the applesauce. Mix the pellets with t he applesauce and swallow the entire tablespoonful of applesauce and Nexium pellets immediately. Do not chew the pellets in the applesauce and do not save the pellets and applesauce for another dose
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Nexium exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Overdose
Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

Significant Interactions:
If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.


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