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How should this medicine be used?
Take Nexium at least one hour before meals. Be careful to swallow it whole. If you have trouble swallowing capsules, you can open the capsule and carefully pour the pellets onto one tablespoon of appl esauce. The applesauce should not be hot. Mix in the pellets, then swallow the applesauce immediately, without chewing.

Side Effects of This Medicine
More common side effects may include:
Abdominal pain, diarrhea, headache

Possible food and drug interactions when taking this medication
If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.

Why is this drug prescribed?
Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)+m-a condition known as gastroesophageal reflux disease. It is also pre scribed to heal the damage (erosive esophagitis) that reflux disease can cause.

Prescribed in combination with the antibiotics Biaxin and Amoxil, Nexium is also used to treat the infection t hat causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach).

Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.

Overdose
Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

What special precautions should I follow?
Breast-feedingˇXIt is not known whether Nexium passes in human breast milk. Since this medicine has been shown to cause unwanted effects in animals, it may be necessary for you to take another medicin or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.


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