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Special warnings about this medication
Do not take Paxil if you have taken a monoamine oxidase (MAO) inhibitor (furazolidone, phenelzine, procarbazine, selegiline, tranylcypromine) in the past 2 weeks. Do not start taking an MAO inhibitor
within 2 weeks of stopping Paxil. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, severe con
vulsions, or the serotonin syndrome.
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Symptoms of overdose may include:
No specific antidote is known. Treatment should consist of those general measures employed in the management of overdose with any antidepressant.
The stomach should be emptied either by the
induction of emesis, lavage or both. Following evacuation, 20 to 30 g of activated charcoal may be administered every 4 to 6 hours during the first 24 hours after ingestion. Supportive care with frequ
ent monitoring of vital signs and careful observation is indicated.
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Before Using This Medicine
Pregnancy¡XPaxil has not been well studied in pregnant women. Paxil should only be used during pregnancy if the potential benefit outweighs the potential risk to the baby. Before taking this medicine,
make sure your doctor knows if you are pregnant or if you may become pregnant.
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Possible Side Effect
More common side effects may include:
- Abnormal ejaculation, abnormal orgasm, constipation, decreased appetite, decreased sex drive, diarrhea, dizziness, drowsiness, dry mouth, gas, impotence, m
ale and female genital disorders, nausea, nervousness, sleeplessness, sweating, tremor, weakness, vertigo
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What is this Drug
Paxil is also prescribed for posttraumatic stress disorder--a crippling condition that sometimes develops in reaction to a disastrous or horrifying experience. Symptoms, which stubbornly refuse to aba
te, include unwanted memories and dreams, intense distress when confronted with reminders of the event, a general numbing of interest and enjoyment, jumpiness, irritability, poor sleep, and loss of co
ncentration.
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Significant Interactions:
Geriatrics: - Administration of paroxetine to the elderly is associated with increased plasma levels and prolongation of the elimination half-life relative to younger adults (see Pharmacology, Pharmac
okinetics). Elderly patients should be initiated and maintained at the lowest daily dose of paroxetine which is associated with clinical efficacy.
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