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Why is this drug prescribed?
Paxil (pa-ROX-uh-teen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder (also known as social phobia), premenstr
ual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD).
Paxil belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). These medicines are th
ought to work by increasing the activity of the chemical serotonin in the brain.
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How to Use
Swallow the controlled-release tablets whole; do not split, chew, or crush them.
Continue to take Paxil even if you feel well. Do not stop taking Paxil without talking to your doctor, especia
lly if you have taken large doses for a long time. Your doctor will probably want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt
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Other Medicines
Anticoagulants: - Paroxetine should be administered with great caution to patients receiving oral anticoagulants. Preliminary data suggest that a pharmacodynamic interaction between paroxetine and war
farin may result in increased bleeding in the presence of unaltered prothrombin times.
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Special Wanring
Cardiovascular: - Frequent: Hypertension, syncope, tachycardia. Infrequent: Bradycardia, conduction abnormalities, ECG abnormal, hypotension, migraine, ventricular extrasystoles. Rare: Angina pectoris
, arrhythmia, atrial arrhythmia, atrial fibrillation, bundle branch block, cerebral ischemia, cerebrovascular accident, congestive heart failure, extrasystoles, low cardiac output, myocardial infarct,
myocardial ischemia, pallor, phlebitis, pulmonary embolus, supraventricular extrasystoles, thrombosis, varicose vein, vascular headache.
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Overdosage
Overdose attempts have been reported with paroxetine; up to 850 mg alone and in combination with other agents. In cases where paroxetine was used alone, no deaths have occurred and recovery was medica
lly uneventful.
Symptoms of overdosage with paroxetine include nausea, vomiting, tremor, dilated pupils, dry mouth and irritability. There are no reports of ECG abnormalities, coma or convul
sions following overdosage with paroxetine alone.
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Precautions while Using this Medicine
Do not suddenly stop taking your Paxil. If you have been instructed to stop taking Paxil, ask you healthcare professional how to slowly decrease the dose. This is to decrease the chance of having disc
ontinuation symptoms such as agitation, breathing problems, chest pain, confusion, diarrhea, dizziness or light-headedness, fast heartbeat, headache, increased sweating, muscle pain, nausea, restlessn
ess, runny nose, trouble in sleeping, trembling or shaking, unusual tiredness or weakness, vision changes, or vomiting.
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