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Possible food and drug interactions
Combining Prozac with MAO inhibitors or Mellaril (thioridazine) is dangerous.
Do not drink alcohol while taking this medication.
It is especially important to check with your docto
r before combining Prozac with the following:
- Alprazolam (Xanax)
- Carbamazepine (Tegretol)
- Clozapine (Clozaril)
- Diazepam (Valium)
- Digitoxin (Crystodigin)
-
Drugs that impair brain function, such as sleep aids and narcotic painkillers
- Flecainide (Tambocor)
- Haloperidol (Haldol)
- Lithium (Eskalith)
- Other antidepressants (Elavil) <
br> - Phenytoin (Dilantin)
- Pimozide (Orap)
- Tryptophan
- Vinblastine (Velban)
- Warfarin (Coumadin)
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How to Use
Prozac should be taken exactly as prescribed by your doctor.
Prozac usually is taken once or twice a day. To be effective, it should be taken regularly. Make a habit of taking it at the same
time you do some other daily activity.
It may be 4 weeks before you feel any relief from your depression, but the drug's effects should last about 9 months after a 3-month treatment regimen
. For obsessive-compulsive disorder, the full effect may take 5 weeks to appear.
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Overdosage
Establish and maintain an airway; ensure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be con
sidered in treating overdose.
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Side Effects of This Medicine
Side effects from Prozac are common:
- upset stomach
- drowsiness
- weakness or tiredness
- excitement or anxiety
- insomnia
- nightmares
- dry mouth
- ski
n more sensitive to sunlight than usual
- changes in appetite or weight
Tell your doctor if any of these symptoms are severe or do not go away:
- constipation
- difficult
y urinating
- frequent urination
- blurred vision
- changes in sex drive or ability
- excessive sweating
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Special Wanring
Serious, sometimes fatal, reactions have been known to occur when Prozac is used in combination with other antidepressant drugs known as MAO inhibitors, including Nardil and Parnate; and when Prozac i
s discontinued and an MAO inhibitor is started. Never take Prozac with one of these drugs or within at least 14 days of discontinuing therapy with one of them; and allow 5 weeks or more between stoppi
ng Prozac and starting an MAO inhibitor. Be especially cautious if you have been taking Prozac in high doses or for a long time.
If you are taking any prescription or nonprescription drugs,
notify your doctor before taking Prozac.
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Other Medicines
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil
], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])¡XHigher blood levels of these medicines may occur, which increases the chance of having serious side e
fects. Your doctor may want to see you more often and may need to change the doses of your medicines. Also, taking amitriptyline, clomipramine, or imipramine with fluoxetine may increase the chance of
developing the serotonin syndrome
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