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Special Wanring
Serious, sometimes fatal, reactions have been known to occur when Prozac is used in combination with other antidepressant drugs known as MAO inhibitors, including Nardil and Parnate; and when Prozac i
s discontinued and an MAO inhibitor is started. Never take Prozac with one of these drugs or within at least 14 days of discontinuing therapy with one of them; and allow 5 weeks or more between stoppi
ng Prozac and starting an MAO inhibitor. Be especially cautious if you have been taking Prozac in high doses or for a long time. If you are taking any prescription or nonprescription drugs,
notify your doctor before taking Prozac.
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How to Use
Prozac comes as a capsule, tablet, and liquid to take by mouth. It is usually taken once or twice a day and may be taken with or without food. Follow the directions on your prescription label carefull
y, and ask your doctor or pharmacist to explain any part you do not understand. Take Prozac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Prozac oral liquid comes with a specially marked dropper for measuring the dose. Ask your pharmacist to show you how to use the dropper. Dilute the liquid in 4 ounces (120 ml) of water, apple j
uice, or Gatorade just before taking it.
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Precautions
Geriatrics: - Elderly patients should initially receive fluoxetine in low dosage with slow progressive increases only if required and tolerated. Patients who have concomitant systemic illnesses or who
are receiving other drugs concomitantly should be under careful observation at all dosage levels.
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What side effects can this medication cause?
Side effects from Prozac are common: - upset stomach - drowsiness - weakness or tiredness - excitement or anxiety - insomnia - nightmares - dry mouth - ski
n more sensitive to sunlight than usual - changes in appetite or weight Tell your doctor if any of these symptoms are severe or do not go away: - constipation - difficult
y urinating - frequent urination - blurred vision - changes in sex drive or ability - excessive sweating
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Significant Interactions:
Venlafaxine (e.g., Effexor)¡XUsing these medicines with fluoxetine or within 5 weeks of stopping fluoxetine may increase the chance of developing a rare, but very serious, unwanted effect known as the
serotonin syndrome. This syndrome may cause confusion, diarrhea, fever, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking
, or twitching. If you develop these symptoms contact your doctor as soon as possible. Taking tramadol with fluoxetine increases the chance of having convulsions (seizures). Also, taking tryptophan wi
th fluoxetine may result in increased agitation or restlessness and intestinal or stomach problems
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Overdose
Any medication taken in excess can have serious consequences. An overdose of Prozac can be fatal. In addition, combining Prozac with certain other drugs can cause symptoms of overdose. If you suspect
an overdose, seek medical attention immediately. Common symptoms of Prozac overdose include: Nausea, rapid heartbeat, seizures, sleepiness, vomiting Other symptoms of Prozac ov
erdose include: Coma, delirium, fainting, high fever, irregular heartbeat, low blood pressure, mania, rigid muscles, sweating, stupor
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