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Significant Interactions:
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil
], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])¡XHigher blood levels of these medicines may occur, which increases the chance of having serious side e
fects. Your doctor may want to see you more often and may need to change the doses of your medicines. Also, taking amitriptyline, clomipramine, or imipramine with fluoxetine may increase the chance of
developing the serotonin syndrome
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Adverse Effects
Allergic or Toxic:
Frequent: Rash, pruritus.
Infrequent: Chills and fever, urticaria, maculopapular rash.
Rare: Allergic reaction, erythema multiforme, vesiculobullous rash, se
rum sickness, contact dermatitis, erythema nodosum, purpuric rash, leukocytoclastic vasculitis, leukopenia, thrombocythemia, arthralgia, angioedema, bronchospasm, lung fibrosis, allergic alveolitis, l
arynx edema, respiratory distress.
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What is this Drug
In addition, Prozac is used to treat panic disorder, including panic associated with agoraphobia (a severe fear of being in crowds or public places). People with panic disorder usually suffer from pan
ic attacks--feelings of intense fear that develop suddenly, often for no reason. Various symptoms occur during the attacks, including a rapid or pounding heartbeat, chest pain, sweating, trembling, an
d shortness of breath.
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Possible Side Effect
If you experience any of the following symptoms, call your doctor immediately:
- jaw, neck, and back muscle spasms
- slow or difficult speech
- shuffling walk
- persistent, fi
ne tremor or inability to sit still
- fever, chills, sore throat, or flu-like symptoms
- difficulty breathing or swallowing
- severe skin rash or hives
- yellowing of the skin or e
yes
- irregular heartbeat
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Other medical problems
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to Prozac. Also tell your health care professional if you are allergic to any other substances, such as foods, preserv
tives, or dyes.
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Overdosage
Nausea and vomiting were prominent in overdoses involving higher fluoxetine doses. Other prominent symptoms of overdose included agitation, restlessness, hypomania, and other signs of CNS excitation,
including seizures.
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