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Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral ¡XMay increase chance of getting severe dryness or redness of skin

Special warnings about this medication
During the first 3 weeks you are using Retin-A, your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full imp rovement of your acne, even if you use the medicine every day. Check with your health care professional at any time skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks .

You should avoid washing the skin treated with Retin-A for at least 1 hour after applying it.

Avoid using any topical medicine on the same area within 1 hour before or after using Retin-A. Otherwise, Retin-A may not work properly or skin irritation might occur.

How should you take this medication?
The presence of other medical problems may affect the use of Retin-A. Make sure you tell your doctor if you have any other medical problems, especially:
- Dermatitis, seborrheic or
- Eczema or
- Sunburn¡XUse of this medicine may cause or increase the irritation associated with these problems

What is this medicine
Use only nonmedicated cosmetics on cleansed skin. Do not use topical preparations with a lot of alcohol, menthol, spices, or lime (e.g., shaving lotions, astringents, and perfumes); they can sting you r skin, especially when you first use Retin-A.

What special precautions should I follow?
Older adults¡XMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause differ nt side effects or problems in older people. There is no specific information comparing use of Retin-A in patients 50 years of age and older with use in other age groups.

Why is this drug prescribed?
Retin-A is used to treat acne. It works partly by keeping skin pores clear.

One of the Retin-A creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Retin-A works bes t when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.


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