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special dietary instructions
Follow the diet program your doctor has given you. You should evenly divide your daily intake of fat, carbohydrates, and protein over three main meals. If Xenical is taken with a meal very high in fat (30% total daily calories from fat), you may experience more side effects from the medication.

Xenical blocks your body's uptake of some fat-soluble vitamins and beta carotene. Therefore, wh en you use Xenical you should take a daily multivitamin supplement that contains vitamins A, E, K, and beta-carotene. Take the vitamin once a day, 2 hours before or 2 hours after taking Xenical, or ta ke the vitamin at bedtime.

Symptoms of overdose may include:
The results of a massive overdose of Xenical are unknown, although the drug seems relatively harmless. However, any medication taken in excess can have serious consequences. If you suspect an overdose , seek medical attention.

What special precautions should I follow?
Before taking Xenical,

tell your doctor and pharmacist if you are allergic to Xenical or any other drugs.
tell your doctor if you have or have ever had anorexia nervosa or bulimia, galls tones, thyroid disease, diabetes, kidney problems, or if you consistently have problems absorbing food (malabsorption syndrome).
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.

How to Use
Take a capsule of Xenical during, or up to 1 hour after, each main meal. You should follow a nutritionally balanced, low-calorie diet that provides no more than 30 percent of its calories from fat. If you miss a meal, or the meal contains no fat, you can skip the accompanying dose of Xenical.

What side effects may occur?
More common side effects may include:
- Abdominal discomfort or pain, anxiety, arthritis, back pain, diarrhea, dizziness, earache, fatigue, fatty or oily stools, fecal urgency or incontinence, fl u, gas with fecal discharge, gum problems, headache, increased defecation, menstrual problems, muscle pain, nausea, oily discharge, rectal discomfort or pain, respiratory tract infections, skin rash, sleep problems, tooth problems, urinary tract infections, vaginal inflammation, vomiting

Less common side effects may include:
- Dry skin, ear/nose/throat problems, joint disorders
< br> Side effects that usually occur after the first year of treatment with Xenical include: depression, leg pain, swollen feet, and tendonitis.

Possible food and drug interactions
If Xenical is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Xenical with the fo llowing:

- Cyclosporine (Neoral and Sandimmune)
- Warfarin (Coumadin)


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