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Special warnings about this medication
This medicine may cause some people to become drowsy, dizzy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangero us if you are dizzy or are not alert and clearheaded.

How should this medicine be used?
Take acetaminophenbutalbitalcaffeine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose withful l glass of water. Take acetaminophenbutalbitalcaffeine with food or milk if it upsets your stomach. Never take more acetaminophenbutalbitalcaffeine than is prescribed for you. If your pain is not bein g adequately treated, talk to your doctor. Store acetaminophenbutalbitalcaffeine at room temperature away from moisture and heat.

What special precautions should I follow?
PregnancyˇX

- For butalbital: Barbiturates such as butalbital have been shown to increase the chance of birth defects in humans. Also, one study in humans has suggested that barbiturates tak n during pregnancy may increase the chance of brain tumors in the baby.Butalbital may cause breathing problems in the newborn baby if taken just before or during delivery.
- For acetaminophen: Al though studies on birth defects with acetaminophen have not been done in pregnant women, it has not been reported to cause birth defects or other problems.
- For caffeine: Use of large amounts of caffeine during pregnancy may cause problems with the heart rhythm and the growth of the fetus.

Side Effects of This Medicine
Check with your doctor immediately if any of the following side effects occur, especially if several of them occur together:

Bleeding or crusting sores on lips; chest pain; fever with or wi thout chills; hive-like swellings (large) on eyelids, face, lips, and/or tongue ; muscle cramps or pain; red, thickened, or scaly skin; shortness of breath, troubled breathing, tightness in chest, or wheezing; skin rash, itching, or hives; sores, ulcers, or white spots in mouth (painful); sore throat

Possible food and drug interactions when taking this medication
When you are taking a butalbital and acetaminophen combination, it is especially important that your health care professional know if you are taking any of the following:

- Anticoagulants (b lood thinners), or
- Carbamazepine (e.g., Tegretol) or
- Contraceptives, oral (birth control pills) containing estrogen, or
- Corticosteroids (cortisone-like medicines) or
- Cortic otropin (e.g., ACTH)ˇXButalbital may make these medicines less effective

Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.


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