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Symptoms of overdose
Symptoms of overdose--may be more severe than side effects occurring at regular doses or several may occur together

- Anxiety ; drowsiness; nausea; serotonin syndrome (diarrhea, fever, in creased sweating, mood or behavior changes, overactive reflexes, racing heartbeat, restlessness, shivering or shaking); unusually fast heartbeat; unusually large pupils; vomiting

How should you take this medication?
Zoloft comes as a tablet and concentrate to take by mouth. It is usually taken once daily and may be taken with or without food. Follow the directions on your prescription label carefully, and ask you r doctor or pharmacist to explain any part you do not understand. Take Zoloft exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continu e to take Zoloft even if you feel well. Do not stop taking Zoloft without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease y our dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

What Is It
Zoloft is a member of the family of drugs called "selective serotonin re-uptake inhibitors." Serotonin is one of the chemical messengers believed to govern moods. Ordinarily, it is quickly reabsorbed after its release at the junctures between nerves. Re-uptake inhibitors such as Zoloft slow this process, thereby boosting the levels of serotonin available in the brain.

Before Taking This Medicine
When you are taking Zoloft, it is especially important that your health care professional know if you are taking any of the following:

- Venlafaxine (e.g., Effexor)¡XUsing these medicines th Zoloft may increase the chance of developing a rare, but very serious, unwanted effect known as the serotonin syndrome. This syndrome may cause confusion, diarrhea, fever, poor coordination, restle ssness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking, or twitching. If you develop these symptoms, contact your doctor as soon as possible
- Dig itoxin (e.g., Crystodigin)

Possible Side Effect
If you experience any of the following symptoms, call your doctor immediately:
- jaw, neck, and back muscle spasms
- slow or difficult speech
- shuffling walk
- persistent fine tre mor or inability to sit still
- fever, chills, sore throat, or flu-like symptoms
- difficulty breathing or swallowing
- severe skin rash
- yellowing of the skin or eyes
- irre gular heartbeat

Special Wanring
Gastrointestinal Disorders: - Infrequent: Dysphagia, eructation. Rare: Diverticulitis, fecal incontinence, gastritis, gastroenteritis, glossitis, gum hyperplasia, hemorrhoids, hiccup, melena, hemorrha gic peptic ulcer, proctitis, stomatitis, ulcerative stomatitis, tenesmus, tongue edema, tongue ulceration.


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